:root {
  --bg: #f7f8f7;
  --panel: #ffffff;
  --ink: #151817;
  --muted: #64706b;
  --line: #dfe5e1;
  --accent: #126b5b;
  --accent-2: #b14b36;
  --cds: #126b5b;
  --exon: #9eb6ae;
  --utr: #d9a441;
}

* {
  box-sizing: border-box;
}

body {
  margin: 0;
  background: var(--bg);
  color: var(--ink);
  font-family: Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;
  font-size: 16px;
  line-height: 1.5;
}

.shell {
  width: min(1180px, calc(100% - 32px));
  margin: 32px auto;
}

.hidden {
  display: none !important;
}

.top-nav {
  position: sticky;
  top: 0;
  z-index: 20;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 24px;
  min-height: 68px;
  padding: 10px max(24px, calc((100vw - 1180px) / 2 + 16px));
  border-bottom: 1px solid var(--line);
  background: rgba(247, 248, 247, .94);
  backdrop-filter: blur(12px);
}

.nav-brand {
  display: grid;
  justify-items: start;
  gap: 1px;
  height: auto;
  padding: 0;
  border-radius: 0;
  background: transparent;
  color: var(--ink);
  text-align: left;
}

.brand-mark {
  font-size: 22px;
  font-weight: 850;
  line-height: 1;
  letter-spacing: 0;
}

.brand-sub {
  color: var(--muted);
  font-size: 12px;
  font-weight: 650;
  text-transform: uppercase;
  letter-spacing: .08em;
}

.nav-menu {
  display: flex;
  align-items: stretch;
  gap: 4px;
}

.nav-link {
  height: 42px;
  padding: 0 13px;
  border-radius: 6px;
  background: transparent;
  color: var(--ink);
  font-size: 15px;
}

.nav-anchor {
  display: inline-flex;
  align-items: center;
  text-decoration: none;
}

.nav-link:hover,
.nav-dropdown:focus-within > .nav-link,
.nav-dropdown:hover > .nav-link,
.nav-brand:hover {
  background: #e9eeeb;
}

.nav-dropdown {
  position: relative;
}

.nav-dropdown::after {
  content: "";
  position: absolute;
  top: 100%;
  right: 0;
  display: none;
  width: 100%;
  height: 10px;
}

.nav-dropdown:hover::after,
.nav-dropdown:focus-within::after {
  display: block;
}

.dropdown-menu {
  position: absolute;
  top: calc(100% + 8px);
  right: 0;
  display: none;
  min-width: 190px;
  padding: 6px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--panel);
  box-shadow: 0 14px 36px rgba(21, 24, 23, .12);
}

.nav-dropdown:hover .dropdown-menu,
.nav-dropdown:focus-within .dropdown-menu {
  display: grid;
  gap: 3px;
}

.dropdown-menu button {
  justify-content: flex-start;
  width: 100%;
  height: 36px;
  padding: 0 10px;
  background: transparent;
  color: var(--ink);
  text-align: left;
  font-size: 14px;
}

.dropdown-menu button:hover:not(:disabled) {
  background: #edf5f2;
  color: var(--accent);
}

.dropdown-menu button:disabled {
  color: var(--muted);
  cursor: default;
  opacity: .7;
}

.about-view {
  display: grid;
  gap: 18px;
}

.about-panel {
  display: grid;
  gap: 12px;
  padding: 24px 26px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--panel);
}

.about-panel h2 {
  margin: 10px 0 0;
  font-size: 22px;
  letter-spacing: 0;
}

.about-panel h2:first-child {
  margin-top: 0;
}

.about-panel p {
  max-width: 940px;
  margin: 0;
  font-size: 16px;
  line-height: 1.7;
}

.about-panel a {
  color: var(--accent);
  font-weight: 650;
  text-decoration: underline;
  text-underline-offset: 3px;
}

.about-disclaimer {
  padding: 14px 16px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: #fbfcfb;
  color: var(--muted);
}

.team-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 12px;
  margin-top: 2px;
}

.team-card {
  padding: 16px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: #fbfcfb;
}

.team-card h3 {
  margin: 0 0 12px;
  color: var(--muted);
  font-size: 14px;
  text-transform: uppercase;
  letter-spacing: .08em;
}

.team-card p {
  margin-top: 8px;
  font-size: 15px;
  line-height: 1.6;
}

.team-card p:first-of-type {
  margin-top: 0;
}

.quick-nav {
  position: fixed;
  right: 22px;
  bottom: 22px;
  z-index: 30;
  display: grid;
  gap: 8px;
}

.quick-nav button {
  width: 84px;
  height: 36px;
  border: 1px solid var(--line);
  border-radius: 999px;
  background: rgba(255, 255, 255, .94);
  color: var(--ink);
  box-shadow: 0 10px 28px rgba(21, 24, 23, .12);
  font-size: 13px;
}

.quick-nav button:hover {
  border-color: var(--accent);
  color: var(--accent);
  background: #fbfcfb;
}

.home-view {
  min-height: calc(100vh - 110px);
  display: grid;
  place-items: center;
  align-content: center;
  gap: 28px;
}

.home-head {
  max-width: 980px;
  text-align: center;
}

.brand-line {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 14px;
  flex-wrap: wrap;
}

.home-head h1 {
  font-size: 54px;
}

.beta-badge {
  display: inline-flex;
  align-items: center;
  height: 28px;
  border: 1px solid var(--line);
  border-radius: 999px;
  padding: 0 11px;
  background: #fbfcfb;
  color: var(--accent);
  font-size: 13px;
  font-weight: 780;
  text-transform: uppercase;
  letter-spacing: .08em;
}

.home-intro {
  max-width: 920px;
  margin: 12px auto 0;
  color: var(--muted);
  font-size: 16px;
  line-height: 1.65;
}

.home-intro a {
  color: var(--accent);
  font-weight: 650;
  text-decoration: underline;
  text-underline-offset: 3px;
}

.home-grid {
  width: min(980px, 100%);
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 18px;
}

.home-tile {
  aspect-ratio: 1 / 1;
  width: 100%;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--panel);
  overflow: hidden;
}

.visual-tile {
  display: grid;
  place-items: center;
}

.visual-tile img {
  width: 100%;
  height: 100%;
  object-fit: cover;
}

.action-tile {
  display: grid;
  place-items: center;
  align-content: center;
  gap: 12px;
  height: auto;
  min-height: 0;
  padding: 22px;
  color: var(--ink);
  background: var(--panel);
  text-align: center;
  line-height: 1.2;
  cursor: pointer;
  transition: border-color .15s ease, transform .15s ease, background .15s ease;
}

.action-tile:hover {
  border-color: var(--accent);
  background: #fbfcfb;
  transform: translateY(-2px);
}

.tile-icon {
  position: relative;
  display: grid;
  place-items: center;
  width: 62px;
  height: 62px;
  border: 1px solid var(--line);
  border-radius: 999px;
  color: var(--accent);
  font-size: 38px;
  line-height: 1;
}

.search-icon::before {
  content: "";
  width: 25px;
  height: 25px;
  border: 4px solid currentColor;
  border-radius: 999px;
  transform: translate(-5px, -5px);
}

.search-icon::after {
  content: "";
  position: absolute;
  width: 24px;
  height: 4px;
  border-radius: 999px;
  background: currentColor;
  transform: translate(15px, 16px) rotate(45deg);
}

.similar-icon::before,
.similar-icon::after {
  content: "";
  position: absolute;
  width: 32px;
  height: 18px;
  border: 4px solid currentColor;
  border-left: 0;
  border-radius: 0 999px 999px 0;
}

.similar-icon::before {
  transform: translate(-8px, -7px) rotate(180deg);
}

.similar-icon::after {
  transform: translate(8px, 7px);
}

.tile-title {
  font-size: 24px;
  font-weight: 750;
  letter-spacing: 0;
}

.tile-note {
  color: var(--muted);
  font-size: 15px;
}

.beta-notice {
  width: min(980px, 100%);
  padding: 18px 20px;
  border: 1px solid #d9a441;
  border-left: 5px solid #d9a441;
  border-radius: 8px;
  background: #fffaf0;
  color: var(--ink);
}

.beta-notice strong {
  display: block;
  margin-bottom: 6px;
  font-size: 18px;
}

.beta-notice p {
  margin: 0;
  color: var(--muted);
  font-size: 15px;
  line-height: 1.55;
}

.placeholder-panel {
  margin-top: 24px;
  padding: 28px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--panel);
}

.backHome {
  margin-bottom: 16px;
}

.module-head {
  padding-bottom: 18px;
  border-bottom: 1px solid var(--line);
}

.module-head h1 {
  font-size: 46px;
}

.similar-workflow {
  display: grid;
  gap: 18px;
}

.similar-form {
  display: flex;
  gap: 10px;
  align-items: center;
  flex-wrap: wrap;
  padding: 18px 0;
}

.similar-form input {
  min-width: min(460px, 100%);
  height: 42px;
  border: 1px solid var(--line);
  border-radius: 8px;
  padding: 0 14px;
  background: var(--panel);
  color: var(--ink);
  font: 16px ui-monospace, SFMono-Regular, Menlo, Consolas, monospace;
}

.confirm-panel {
  display: grid;
  gap: 12px;
}

.confirm-card {
  padding: 18px 20px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: var(--panel);
}

.confirm-card h3 {
  margin: 0 0 12px;
  font-size: 19px;
  text-transform: uppercase;
  letter-spacing: .08em;
  color: var(--muted);
}

.protein-choice {
  display: flex;
  gap: 10px;
  align-items: center;
  margin-top: 14px;
  color: var(--muted);
  font-size: 15px;
}

.confirm-actions {
  margin-top: 14px;
}

.candidate-group {
  padding: 0;
  border-top: 1px solid var(--line);
}

.candidate-group h3 {
  margin: 18px 20px 12px;
  font-size: 19px;
  text-transform: uppercase;
  letter-spacing: .08em;
  color: var(--muted);
}

.query-summary {
  display: flex;
  align-items: center;
  gap: 10px;
  flex-wrap: wrap;
  padding: 18px 20px;
  cursor: pointer;
  list-style: none;
  background: #fbfcfb;
}

.query-summary::-webkit-details-marker {
  display: none;
}

.query-summary::before {
  content: "›";
  display: inline-grid;
  place-items: center;
  width: 22px;
  height: 22px;
  border: 1px solid var(--line);
  border-radius: 999px;
  color: var(--accent);
  font-size: 18px;
  transform: rotate(0deg);
}

.candidate-group[open] .query-summary::before {
  transform: rotate(90deg);
}

.query-title {
  font-size: 25px;
  font-weight: 780;
  color: var(--ink);
}

.query-pill {
  display: inline-flex;
  align-items: center;
  min-height: 28px;
  border: 1px solid var(--line);
  border-radius: 999px;
  padding: 0 11px;
  color: var(--muted);
  font-size: 13px;
}

.pair-domain-section {
  margin: 18px 20px 20px;
  display: grid;
  gap: 12px;
}

.pair-domain-section h4 {
  margin: 0;
  font-size: 18px;
  text-transform: uppercase;
  letter-spacing: .08em;
  color: var(--muted);
}

.pair-domain-map {
  width: 100%;
  max-width: 980px;
  min-height: 150px;
  border: 1px solid var(--line);
  border-radius: 6px;
  background: #fbfcfb;
}

.domain-matrix-wrap {
  overflow-x: auto;
}

.domain-matrix {
  min-width: 620px;
}

.domain-matrix th,
.domain-matrix td {
  text-align: center;
}

.domain-matrix th:first-child,
.domain-matrix td:first-child {
  text-align: left;
}

.domain-matrix-row {
  cursor: pointer;
}

.domain-matrix-row.active {
  background: #edf5f2;
}

.identity-cell {
  width: 82px;
  height: 32px;
  border-radius: 6px;
  padding: 0 8px;
  color: var(--ink);
  font-size: 14px;
  font-weight: 700;
}

.identity-high {
  background: #2d7a62;
  color: #fff;
}

.identity-mid {
  background: #8fc1a9;
}

.identity-low {
  background: #d3e7dc;
}

.identity-weak {
  background: #eef4f1;
}

.identity-none {
  background: #f0f2f1;
  color: var(--muted);
}

.domain-detail {
  display: grid;
  gap: 12px;
  padding: 12px;
  border: 1px solid var(--line);
  border-radius: 6px;
  background: #fbfcfb;
}

.candidate-buttons {
  display: flex;
  flex-wrap: wrap;
  gap: 8px;
  padding: 18px 20px;
}

.candidate-buttons button {
  height: 34px;
  padding: 0 12px;
  font-size: 14px;
}

.search-panel {
  display: grid;
  grid-template-columns: 240px 1fr;
  gap: 32px;
  align-items: start;
  padding-bottom: 24px;
  border-bottom: 1px solid var(--line);
}

h1 {
  margin: 0;
  font-size: 42px;
  line-height: 1;
  letter-spacing: 0;
}

p {
  margin: 8px 0 0;
  color: var(--muted);
}

textarea {
  width: 100%;
  min-height: 128px;
  resize: vertical;
  border: 1px solid var(--line);
  border-radius: 8px;
  padding: 14px 16px;
  background: var(--panel);
  color: var(--ink);
  font: 16px/1.5 ui-monospace, SFMono-Regular, Menlo, Consolas, monospace;
}

button {
  height: 40px;
  border: 0;
  border-radius: 6px;
  padding: 0 16px;
  background: var(--accent);
  color: #fff;
  font: inherit;
  font-size: 15px;
  font-weight: 650;
  cursor: pointer;
}

button.secondary {
  background: #e9eeeb;
  color: var(--ink);
}

.file-button {
  display: inline-flex;
  align-items: center;
  height: 40px;
  border-radius: 6px;
  padding: 0 14px;
  background: #e9eeeb;
  color: var(--ink);
  font-size: 15px;
  font-weight: 650;
  cursor: pointer;
}

.file-button input {
  display: none;
}

.similarity-meta button,
.tree-actions button,
.report-actions button {
  height: 34px;
  padding: 0 12px;
  font-size: 14px;
}

.controls {
  display: flex;
  align-items: center;
  gap: 10px;
  margin-top: 12px;
  flex-wrap: wrap;
}

#status,
.search-limit {
  color: var(--muted);
  font-size: 15px;
}

.results {
  display: grid;
  gap: 18px;
  margin-top: 22px;
}

.site-footer {
  margin: 28px 0 0;
  padding-top: 18px;
  border-top: 1px solid var(--line);
  color: var(--muted);
  font-size: 13px;
}

.gene-card {
  background: var(--panel);
  border: 1px solid var(--line);
  border-radius: 8px;
  overflow: hidden;
}

.gene-head {
  display: flex;
  justify-content: space-between;
  gap: 16px;
  padding: 18px 20px;
  border-bottom: 1px solid var(--line);
}

.gene-title {
  display: flex;
  align-items: baseline;
  gap: 12px;
  flex-wrap: wrap;
}

.gene-title h2 {
  margin: 0;
  font-size: 28px;
  letter-spacing: 0;
}

.tag {
  display: inline-flex;
  align-items: center;
  min-height: 26px;
  border: 1px solid var(--line);
  border-radius: 999px;
  padding: 0 11px;
  color: var(--muted);
  font-size: 13px;
}

.multi-panel {
  background: var(--panel);
  border: 1px solid var(--line);
  border-radius: 8px;
  overflow: hidden;
}

.multi-head {
  display: flex;
  justify-content: space-between;
  gap: 16px;
  align-items: flex-start;
  padding: 18px 20px;
  border-bottom: 1px solid var(--line);
}

.multi-head h2 {
  margin: 0;
  font-size: 30px;
  letter-spacing: 0;
}

.table-wrap {
  overflow-x: auto;
}


.multi-panel > .table-wrap {
  padding: 0 20px 18px;
}

.multi-panel > .note {
  margin: 12px 20px 18px;
}

.candidate-group > .table-wrap {
  padding: 0 20px 18px;
}

.candidate-group > .tree-actions,
.candidate-group > .tree,
.candidate-group > .empty,
.candidate-group > .note {
  margin-left: 20px;
  margin-right: 20px;
}

.candidate-group > .tree {
  width: calc(100% - 40px);
}

.multi-table th,
.multi-table td {
  white-space: nowrap;
}

.multi-table tbody tr {
  cursor: default;
}

.multi-table tbody tr.active {
  background: #edf5f2;
}

.multi-table .viewReport {
  height: 32px;
  padding: 0 12px;
  font-size: 13px;
}

.selected-report {
  display: grid;
  gap: 18px;
}

.multi-missing {
  display: flex;
  flex-wrap: wrap;
  gap: 8px;
  padding: 12px 20px 16px;
}

.error-inline {
  color: var(--accent-2);
  font-size: 13px;
}

.search-note {
  padding: 12px 14px;
  border: 1px solid var(--line);
  border-radius: 8px;
  background: #fbfcfb;
  color: var(--muted);
  font-size: 15px;
}

.sections {
  display: grid;
  grid-template-columns: 1fr;
}

.block {
  padding: 18px 20px;
  border-bottom: 1px solid var(--line);
}

.block h3 {
  margin: 0 0 12px;
  font-size: 19px;
  text-transform: uppercase;
  letter-spacing: .08em;
  color: var(--muted);
}

.link-button {
  height: auto;
  border: 0;
  border-radius: 0;
  padding: 0;
  background: transparent;
  color: var(--accent);
  font-weight: 780;
  text-decoration: underline;
  text-underline-offset: 3px;
}

.link-button:hover {
  color: #0b4f42;
}

.report-actions {
  display: flex;
  gap: 8px;
  flex-wrap: wrap;
  margin-bottom: 12px;
}

.kv {
  display: grid;
  grid-template-columns: 120px 1fr;
  gap: 8px 14px;
  font-size: 15px;
}

.kv span:nth-child(odd) {
  color: var(--muted);
}

.model {
  width: 100%;
  height: auto;
  min-height: 120px;
  border: 1px solid var(--line);
  border-radius: 6px;
  background: #fbfcfb;
}

.legend {
  display: flex;
  gap: 14px;
  flex-wrap: wrap;
  margin-top: 10px;
  color: var(--muted);
  font-size: 13px;
}

.swatch {
  display: inline-block;
  width: 12px;
  height: 12px;
  border-radius: 3px;
  margin-right: 5px;
  vertical-align: -2px;
}

.expr-controls,
.seq-controls {
  display: flex;
  gap: 10px;
  align-items: center;
  flex-wrap: wrap;
  margin-bottom: 12px;
}

select,
input[type="range"] {
  accent-color: var(--accent);
}

.chart {
  width: 100%;
  min-height: 210px;
  max-width: 760px;
}

.seq {
  max-height: 260px;
  overflow: auto;
  white-space: pre-wrap;
  word-break: break-all;
  border: 1px solid var(--line);
  border-radius: 6px;
  padding: 12px;
  background: #fbfcfb;
  font: 13px/1.7 ui-monospace, SFMono-Regular, Menlo, Consolas, monospace;
}

.seq .cds {
  background: rgba(18, 107, 91, .24);
}

.seq .exon {
  background: rgba(158, 182, 174, .55);
}

.seq .utr {
  background: rgba(217, 164, 65, .42);
}

table {
  width: 100%;
  border-collapse: collapse;
  font-size: 15px;
}

th,
td {
  border-bottom: 1px solid var(--line);
  padding: 10px 8px;
  text-align: left;
  vertical-align: top;
}

th {
  color: var(--muted);
  font-weight: 650;
}

.empty,
.error {
  padding: 18px 20px;
  color: var(--muted);
}

.error {
  color: var(--accent-2);
}

.similarity-meta {
  display: flex;
  gap: 8px;
  flex-wrap: wrap;
  margin-bottom: 12px;
}

.tree-title {
  margin-top: 20px !important;
  font-size: 19px !important;
}

.tree-actions {
  display: flex;
  gap: 8px;
  margin: 0 0 10px;
}

.tree {
  width: 100%;
  max-width: 980px;
  min-height: 220px;
  border: 1px solid var(--line);
  border-radius: 6px;
  background: #fbfcfb;
}

.domain-map {
  width: 100%;
  max-width: 980px;
  min-height: 120px;
  margin-bottom: 12px;
  border: 1px solid var(--line);
  border-radius: 6px;
  background: #fbfcfb;
}

.newick {
  margin-top: 10px;
  color: var(--muted);
  font-size: 15px;
}

.newick pre {
  white-space: pre-wrap;
  word-break: break-all;
  color: var(--ink);
}

.note {
  margin: 8px 0 12px;
  color: var(--muted);
  font-size: 13px;
}

@media (max-width: 820px) {
  .top-nav {
    align-items: flex-start;
    flex-direction: column;
    gap: 10px;
    padding: 10px 16px;
  }

  .nav-menu {
    width: 100%;
    overflow-x: auto;
  }

  .dropdown-menu {
    left: 0;
    right: auto;
  }

  .team-grid {
    grid-template-columns: 1fr;
  }

  .home-view {
    min-height: auto;
  }

  .home-grid {
    grid-template-columns: 1fr;
  }

  .brand-line {
    gap: 10px;
  }

  .home-head h1 {
    font-size: 44px;
  }

  .home-intro {
    font-size: 15px;
    text-align: left;
  }

  .search-panel {
    grid-template-columns: 1fr;
  }

  .quick-nav {
    right: 14px;
    bottom: 14px;
  }

  .quick-nav button {
    width: 76px;
    height: 34px;
    font-size: 12px;
  }

  .gene-head {
    flex-direction: column;
  }
}